Tracking Down of a Selected Panel of Parabens: A Validated Method to Evaluate Their Occurrence in Skin Layers

A method was set up and validated to identify quantify seven parabens in each of the three skin layers, i.e., Stratum Corneum, Epidermis, Dermis, because, even if only some analogues are legally allowed Europe, forbidden also detected many personal care products therefore can be absorbed by skin. solid/liquid extraction followed a gradient elution chromatographic separation performed according European guidelines. Our afforded detection all with limit values ranging from 0.026 0.090 ?g mL?1 recoveries 61.80 105.73 at high low concentration (50.0–5.0 mL?1), respectively. The proposed help assess paraben’s bioaccumulation since people repeatedly exposed consumer goods containing their daily routine, posing chronic risk human health.